Welcome Polygenically Screened Babies

On the birth of the first polygenically-screened baby (Aurea, via LifeView / Steve Hsu). Explains polygenic embryo screening: IVF produces many embryos, whole-genome sequencing predicts polygenic disease risk (schizophrenia, breast cancer), and you implant the lowest-risk one -- or use 'genomic indexing' to minimize overall serious-disease risk weighted by likelihood/severity. The pitch: if you're doing IVF you must choose an embryo anyway, so why not halve serious-disease risk for ~$1,400? Then the designer-baby / IQ questions (screening companies give you raw data; Gwern's calc of +3 IQ now, +9 at the tech's limit with 10 embryos), and the prediction-market 'wait 15 years' caveat.

Quality 65 · Strong. Strong (low): a clear, informative explainer of an important emerging technology (polygenic embryo selection) with the good 'you're choosing an embryo anyway' framing, but short and largely news-relaying.

Claude’s paradigm shift 45 · Moderate. Moderate: conveys an emerging practice; the genomic-indexing framing is a nice angle but not a novel idea of Scott's.

Real-world impact 2 · Minor. Minor: covers a real, growing practice with material stakes, but the post itself is a news/explainer.